FiRe CTO Design Challenge: “Creating the New Field of Medicine: ‘Nutritional Microanalysis’: Inputs for the Quantified Self”

Hosted and judged by Mark Anderson; with David Brin, Author and Physicist; Ty Carlson, Architect for BPOS Engineering (R&D)/Office 365, Microsoft; William Harris, President and CEO, Science Foundation Arizona; Sridhar Jagannathan, VP, Technology Strategy and Partnerships, Office of the CTO, Intuit; Eric Openshaw, Vice Chairman and U.S. Technology Leader, Deloitte LLP, and Global Technology Sector Leader, Deloitte; Jerry Woodall, Founder, WoodallTech, and National Medal of Technology Laureate; André de Fusco, CEO and Director, Cynvenio Biosystems; and others TBA

Requests:

“Asking to create new field of medicine: nutritional microanalysis”

1. describe field.

2. What resources will be needed?

3. Can we create technical platform?

4. How do we integrate this into medicine?

5. How can FiRe participants participate?

SJ: Imagine you’re the CEO of the company, Your Body. Balance sheet of your body is extremely complex. Will you be able to predict the balance sheet of your body 3 months from now?

Highly complex, multifaceted system we have no idea about.

Micronutrient Analysis Vectors

1. Ingredient analysis
   1. Oils
   2. vegetables
   3. fruits
2. Processed foods
3. Cooked foods
4. Personal data
5. Internal probes
   1. Digestive cocktail
   2. digestive flora
   3. digestive enzymes
6. external probes
   1. Cameras, proteins, acids
7. Individual consequences
8. social behavior modification

AdF: Metabolic Syndrome is group of risk factors that occur together and increase the risk for coronary artery disease, stroke and type 2 diabetes. 40 million in the US are thought to be at risk

Most is related to food and exercise

Metrics: extra weight around center of our bodies, insulin resistance

Prevention:

• Regular exercise
• Low fat diet, with a variety of fruits, vegetables, whole grain products
• Losing weight (BMI less than 25)
• Managing blood pressure and blood sugar
• Not smoking

Learning

• Understanding: Food ID & basic nutrition guide
• Motivation: Personal goals, economic and social incentives
• Modify Behavior: Shift away from red meats, use social networks, photo of food plate
• Results: weight management, blood sugar, energy level, mood stability
• Technology solution: Smartphone application
• Increase basic knowledge: ingredients, basic nutrition database, conbinations
• Reward behavior: Tracking system, game/tracking system
• Extend knowledge: Nutritious recipes,

New Tech

• Eat well plate: nano plate detects chemical composition of food on the plate
• Nutritional data is reported to your smartphone
• Bioluminescent spray to highlight fats

Extending

• Understanding
• Motivation
• Modify Behavior
• Results
• QR labels on foods, in produce depts
• “Organic labeled foods must include micronutrient info based on soil, fertilizers or food stock
• Smartphone-based probes to sample nutrients, chemicals in foods
• BioChips to measure heart rate, oxygenation, sweat, exercise levels
• Reward behavior: nutritional analysis and tracking information
• Extend knowledge: introduce micronutrients, amino acids, ancient grains

Promising technology

• Micromass spectroscopy
• Microarray chem or chromotography
• Microwave sensors
• image analysis of the dinner plate
• Bio pill: wireless transmission to external device

• Understanding: detailed breakdown of self, tracking multiple inputs/outputs, understanding of nutrients, biochemical interactions, sleep, exercise
• Modify behavior: Primarily leafy greens, fruits, beggies, nuts, limited animal proteins
• Results: Know personal nutrient requirements, design optimized meal plans, proactive selection of optimal foods, tracks results for continual revisions
• Certified Organic labels: detailed nutrition information, source of food, micronutrient breakdown of soils, fertilizers, contaminants and toxins
• Bio Pills: known what is goind on inside for basieline and monitor change, personal nutrition profile
• reward behavior: nutritional analysis and tracking info
• Extend knowledge

Potential solutions

Focused on individual vs. social, available vs innovated technology

Innovative Individual: bio-fork, food analysis plate, enhanced microwave

Available ind: Toxin-detector spray, photo food diary

Social innovation: Ecosystem

Social available: Community-based nutrition review, local food photo club

The 720 View

• Build a personal baseline
• predictive capacity
• 720 view of in/outputs of your body
  • Data samples
  • Before/after meals
  • Blood, stool samples
  • foods analysis
  • DNA analysis
  • exercise data, profile
• Upload to cloud
• Change model to predictive:If you eat this . . .
• Predictive performance
• Nutrition profile partners
• Dial in performance (what if scenarios
• Abstract profiles then aggregate: improve early ID, grouping corrective action
• Nutritional healing
• Drive change in food industry through consumer demand

We already have sensors, we just need to be able to integrate these into socially acceptable measurement devices

Business Opportunity

• Potential industry for 6 billion Me Inc. is huge
• Personal sensors

Business Model Evolution

• Stage 1
  • Platform owner would have business model based on application market
  • analytic service providers pay for access to data and promotion of services
  • Assumption: individuals pay for analytic services that would help maximize wellness based on advertising
• Stage 2
  • Platform evolves and begins to provide a market connecting people and wellness providers
  • transaction feeds generated for the platform owner
• Stage 3
  • Payors and companies participate on the platform pay fees for shared data
  • Share savings in the form of monetary incentives for employees to participate.

Ecosystem Platform

• Develop an ecosystem platform where all participants benefit

Ecosystem Stakeholders

• Orchestrator
  • Aggregate of wellness providers
  • capture individual wellness
• Individuals
• Employers/ large corporations
• Payors
• Providers/nutritionists
• Policymakers
• Suppliers
• Community enablers: Facebook, yelp, opentable, etc
• Tech providers

Summary

• Need to move now, with practical steps
• technologies exist today, with demand they will scale size, cost, convenience
• Cloud enables the scale, scale drives down the costs, makes accessible to the masses
• The Ecosystem Platform components and motivation exists, we need to orchestrate the players
• It’s obvious — you just have to look at it through the right lens

MA: What will lead food companies to label more extensively?

Demand. Driven by Walmart, Whole Foods, etc

Spray toxin detector?

There’s a lot that can be done with neutral particles.